It would appear from Adam's list that the two most followed Mastodon profiles are Eugen Rochko, the developer of Mastodon (@Gargron) and Star Trek actor George Takei (@georgetakei), both with over 200,000 followers.
I also want to stress that I don't believe, in *ANY* way, shape, or form, we should repeat the mistakes of the birdsite, in thinking that the more followers a person has, the more importance, influence, or "clout" they have! But I am a stats nerd, so I found this interesting! ?