@foxy
There are several ways to filter your home timeline. First you can long press the home tab and some filters will be displayed. It is an easy way to hide replies or boosts for example.
Also, from a user profile, you can mute an account only for the home timeline (three dots at the top right).
As it was mandatory to follow an account to add it in a list, #Fedilab also allows to bulk mute from home all users in a list (Main menu > Lists > three dots).
These are Fedilab features only.