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   Nuno & Lua :DsaprvingLua: (ncrav@mas.to)'s status on Thursday, 13-Jun-2024 21:46:32 JST Nuno & Lua :DsaprvingLua:

   #TIL

   TL;DR #Metformin (one of the best type 2 #diabetes drugs) reduces gains and benefits from #exercise in general, and hampers muscle gains specifically. That may explain some things I've noticed lately 🙄

   https://www.science.org/content/blog-post/metformin-and-exercise

   #bodybuilding #workout

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     Nuno & Lua :DsaprvingLua: (ncrav@mas.to)'s status on Thursday, 13-Jun-2024 21:52:37 JST Nuno & Lua :DsaprvingLua:

     • Tokyo Outsider (337ppm)

     @tokyo_0 yes! It's true, it has a lot of health benefits apart from being used for diabetes, also does some wonders for controlled weight loss, in my case due to the hunger inhibition effect that reduces snacking. The thing with muscle growth appears to be related with its anti-inflammatory effects reducing adaptation. Take this with a grain of salt because there's not so much on this, but it makes sense, since many anti-inflammatory drugs (e.g. ibuprofen) have similar effects on muscle growth.

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     Nuno & Lua :DsaprvingLua: (ncrav@mas.to)'s status on Thursday, 13-Jun-2024 22:13:15 JST Nuno & Lua :DsaprvingLua:

     • Tokyo Outsider (337ppm)

     @tokyo_0 yes, and a sufficient degree of inflammation is needed for the process to happen (but not too much because that has the inverse effect).