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    Eric Topol (erictopol@mstdn.social)'s status on Thursday, 30-May-2024 16:56:49 JST Eric Topol Eric Topol

    What if there was an antibiotic that doesn't disrupt the gut microbiome?
    There is now.
    A discovery published at Nature today
    https://nature.com/articles/s41586-024-07502-0

    In conversation about a year ago from mstdn.social permalink

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    1. https://media.mstdn.social/media_attachments/files/112/527/526/144/210/103/original/57b3ab38d5b63402.jpeg
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      A Gram-negative-selective antibiotic that spares the gut microbiome - Nature
      from Hergenrother, Paul J.
      Lolamicin, a novel antibiotic developed from a pyridinepyrazole precursor, exhibits potent activity against a broad range of Gram-negative multidrug-resistant clinical isolates, and good efficacy in mouse models of infection without inducing gut dysbiosis.

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