Yessss! GNU Guix/Hurd builds with rumpdisk, a major step towards running on real iron!
You'll need these patch sets:
* https://issues.guix.gnu.org/63641
* https://issues.guix.gnu.org/63527 (comment #38 has a QEMU example)
or download this image
https://dezyne.org/janneke/c2f2lpvfp05pw2isihgbwx6f1b1l0hwh-disk-image.xz