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Whether vaccines technically work or not is kind of beside the point, they're conceptually broken. In free country, they'd be made by competing businesses that people trust enough to voluntarily take them.
But the whole premise of vaccines is that people are coerced or forced to take them at risk of social exclusion by state power. So they are guaranteed to always be "government quality" crap just good enough to please a bureaucrat - and because it's completely centralized, the risk of supply chain attacks / poison is massive.
Even if they work, states should be forbidden from practicing social exclusion. Drug companies just need to put their thinking caps on and invent something which works WITHOUT relying on totalitarian coercion.