An edited version of The Lady with an Ermine by Leonardo da Vinci. It depicts the top half of a woman turned toward her right but with her face turned toward her left. Instead of an ermine she is holding a teal and white knitted chicken in her arms, looking in the same direction.
https://things.uk/system/media_attachments/files/112/591/649/352/787/260/original/fd66c71433e1de8d.jpg