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   Coach Mark (coachmark@beige.party)'s status on Monday, 10-Jun-2024 22:43:50 JST Coach Mark

   @FlashMobOfOne I know, my question was a bit rhetorical, but why would you go to see anyone speak to sit behind them and stare at their backside for hours.

   So. Fucked. Up.

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   M.S. Bellows, Jr. (msbellows@c.im)'s status on Wednesday, 29-May-2024 14:07:06 JST M.S. Bellows, Jr.

   I'm gonna share some completely anticlimactic TMI for the benefit of other middle-aged men:

   The day before yesterday, I was very stressed and anxious for a variety of reasons, and we were moving some furniture out of a storage locker, and I was feeling lethargic and a little lightheaded and generally out of it, and then I began feeling nausea and indigestion and my jaw was tight and then my left arm and hand started feeling a little numb. Nothing terrible! Just: feeling meh, and those minor symptoms.

   And then guess what crazy thing we did?

   We went to the nearby emergency room.

   Yep.

   And they were very nice to me, and quickly administered an EKG and blood tests, and guess what?

   I *wasn't* having a heart attack.

   I was just stressed and tired and anxious. That's all.

   But if I *had* been having a heart attack, going to the E.R. could have saved my life. And even though I wasn't, they were very nice to me. No one made fun of me. No one called me a whiner or a hypochondriac. My wife expressed gratitude that I took my survival seriously. And I was home again in less than two hours.

   So this is for my fellow typical men, who are inclined to ignore health issues because: John Wayne or something:

   Don't ignore stuff. Don't wait until you're sure. Be willing to overreact. Be willing to waste everyone's time. It's okay! The world won't end! (And you may even get to take a nap under a warm blanket, like I did!)

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   botvolution (botvolution@mastodon.sdf.org)'s status on Thursday, 02-Nov-2023 18:25:48 JST botvolution

   I am awaiting an Inspection Visitation from the lettings agent today and The Landlord wishes to stick her nose in my business too this time.

   I fucking hate this, it feels intrusive & I can't focus on anything else until its over.

   So I'm just going to sit here being irritable, bored & annoyed for a few hours.

   So, thanks, rentier class who will be the first against the wall when The Time comes.

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   CJ Bellwether (siege@octodon.social)'s status on Sunday, 22-Oct-2023 23:32:35 JST CJ Bellwether

   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944393/

   This is most absurd clinical findings ive seen regarding trans females. It states they prescribed "oral estradiol" starting at 2mg and increasing in dose over a year to try and achieve levels above 100 pg/ml with an aim towards monotherapy between 2008 and 2018 looking at 184 trans women in their clinic.

   Looking at their scatter chart they state 1 patient achieved about 90 pg/ml on 1mg oral, 2 patients achieved over 100 pg/ml on 2mg oral, and 14 achieved over 100 pg/ml on 4 mg oral.

   The issue? a patient on 1mg oral will not see estradiol levels above 25 pg/ml at peak, a patient on 2mg oral will not see estradiol levels above 50 pg/ml at peak, and 4mg oral will only break 100 pg/ml at peak at 6-8 hours and then crash below 40 pg/ml after 24 hours.

   So whats going on? well a minority of their patients who somehow magically achieved the impossible, as usual were doing what trans girls in the US do all the time, they take the medication they're given and then took it sublingually (and likely broke up their doses through the day) because you get far higher levels that last longer that way.

   The only other explanation is these patients had their estradiol levels tested incorrectly either not at trough or there was an aberration in the test.