· A large electronic health records study found SARS-CoV-2 infection is associated with elevated risks of Human Papillomavirus (HPV)-related cancer · A small study in the Journal of Translation Medicine found a potential blood test for myalgic encephalomyelitis (ME) · Researchers have developed a device that may be able to accurately measure fibrinaloid microclots in children
· A clinical trial for the anti-inflammatory drug Colchicine did not find the drug effective for #LongCOVID · A white paper from the Patient-Led Research Collaborative assessed Long COVID in India · Researchers recently critiqued the study design and conclusions of a controversial 2024 study on ME, which asserted that the disease was a result of altered “effort preference” and deconditioning
· The #German government is cutting millions of euros in #LongCOVID funding · Large electronic cohort study from Sweden found that 1.4% of people with a documented #COVID19 case were officially diagnosed with Long COVID by medical providers · Lidia Morawska, Australian scientist who alerted the world that SARS-CoV-2 was airborne, was recently recognized for her work with a prestigious science prize for “pioneering research about the air we breathe"
· The RECOVER-NEURO clinical trial found that “cognitive rehabilitation” failed in treating #LongCOVID · Scientists are revealing more about microclots and Long COVID. A recent study in the Journal of Medical Virology found a strong association between microclots and net-like structures that some white blood cells (called neutrophils) release to attack pathogens · A study about #MECFS was retracted by the journal Food Science and Nutrition
· New mechanistic study in Science Translational Medicine identifies Epstein-Barr virus as a potential trigger of the autoimmune disease systemic #lupus erythematosus · Michael Peluso of UCSF shared updates on two upcoming #LongCOVID trials: - One potential trial called COMBAT-LC plans to test the combination of the monoclonal antibody Pemgarda with the antiviral Paxlovid - The second trial INTERRUPT-LC will test the bladder cancer drug Anktiva
· A review paper summarizes the vast global costs of #LongCOVID, it is estimated to have an average annual burden of at least $1 trillion globally per year · A small study in Nature found SARS-CoV-2 in the organs of fetuses from people who were infected with the virus while pregnant · The National Institutes of Health’s RECOVER-Treating Long COVID initiative released a draft of its protocol for the low-dose naltrexone trial for people ages 6-25
· Large retrospective cohort study of over 18,000 births found infants exposed to #COVID19 during pregnancy were more likely to have adverse neurodevelopmental diagnoses as 3 years olds · Another study has found that common diabetes drug metformin may help reduce risk of #LongCOVID · NIH is recruiting for a small observational study to understand if people with neurological symptoms of Long COVID have inactive [?] remnants of SARS-CoV-2 in their bodies
· A new study in the International Journal of Infectious Diseases examines how #COVID19 impacts the immune system · German government announced just over €500 million ($582 million USD) in funding for infection-associated diseases, including #LongCOVID & #MECFS · A preprint using data from the DecodeME study found more than 250 genes associated with ME, 76 of which were shared with Long COVID
· New study in Cureus found veterans diagnosed with #LongCOVID at 34% higher risk of visiting emergency department 6 months after infection · “Our data demonstrate that [LC] is characterized by chronic inflammation, immune exhaustion, & metabolic dysregulation,” scientists conclud in new study published in Nature Immunology · U.K. charity ME Association awards £1.1 million in funding to the Imperial College to study immunological profiles of LC & #MECFS
· Two recent studies state that #LongCOVID is an occupational disease. · Vanderbilt researchers are conducting an immune profiling study on people with Long COVID and postural orthostatic tachycardia syndrome (#POTS) · A new phase two remote clinical trial was recently announced for myalgic encephalomyelitis (ME) #MECFS
· 43% of Latino people reported symptoms of #LongCOVID in a new survey study published in Journal of General Internal Medicine · A case series for Long COVID using a combination of Paxlovid, valacyclovir (Valtrex) and celecoxib (Celebrex), was recently published in Frontiers of Immunology · A new phase II clinical trial for Long COVID was recently announced in the Netherlands
· A large, electronic health records study published in JAMA Internal Medicine estimated that over 100,000 Americans died each year between 2022 and 2024 from #COVID19 · A new study published in Molecular & Cellular Proteomics found further evidence of abnormalities in post-exertional malaise #PEM · A small phase two clinical trial is testing #Ketamine for #LongCOVID fatigue and cognitive function
· A new study in eBioMedicine found neurological #LongCOVID symptoms were associated with increased pTau-181 levels, a marker of brain inflammation tied to Alzheimer’s disease · A new “state-of-the-art” review on #POTS highlighted that the multisystemic condition is disabling, causes societal & economic withdrawal · A phase II clinical trial testing efficacy & safety Uplizna (Inebilizumab) in LC & #MECFS recently announced by German Ministry of Research
· A large prospective cohort study published in Infectious Diseases found that a majority of people with #LongCOVID did not recover · Some researchers in Australia are getting a small boost in Long COVID funding · The biotech company Invivyd is advancing research of a #COVID19 monoclonal antibody called VYD2311, designed to improve upon the currently-available Pemgarda
· The Food and Drug Administration (FDA) has granted expanded access to the stem cell infusion RegeneCyte for #LongCOVID · Long COVID isn’t being consistently captured around the world due to differences in sociological factors, diagnostic tools, and healthcare access · A phase two trial for Long COVID-associated postural orthostatic tachycardia syndrome (#POTS) is testing a product called 2-hydroxybenzylamine (2-HOBA)
· A large study recently connected “chronic absenteeism” to pediatric #LongCOVID, further disproving the “immunity debt” talking points from pundits earlier in the pandemic · A small mechanistic study in Brain, Behavior, & Immunity – Health found that immunoglobulin G (IgG), isolated from people with #MECFS, can destroy mitochondria in endothelial cells · ADDRESS-LC has opened two more study sites: a new one in California and one in Connecticut
· New review in Dovepress states that #LongCOVID, #MECFS & #POTS should be classified as neuroimmune disorders. · Wearable activity tracker notifications may not be a reliable way to mitigate or reduce PEM, new study in Nature Communications · Small, phase one study is recruiting in Sacramento & San Francisco, CA to test advanced techniques in total body imaging to improve understanding of “tissue-level immune dysregulation” in the disease
· SARS-CoV-2 reinfections significantly increase the risk of #LongCOVID in children, a new National Institutes of Health (NIH) RECOVER study found · A large cohort study found further evidence that people with #HIV have a significantly increased risk of Long COVID following SARS-CoV-2 infection · An in-depth whole genome sequencing study called Sequence #MECFS and Long COVID is seeking to raise £20 million ($23.6 million USD) in funding
★ Es gibt nix Gutes, ausser 😷 toot es ★ Boosted means boss move★ Weckt mich wenn Revolution ist★ Alpaca 🦙 Ozelot 🐆 Axolotl 🦎★ Allen alles★ Auf allen Spektren"hard to like"Community care for mental health, mutual aid for all.Life is difficult in these times, feel free to ask me for help. write: D/E/F/ read: Sp/It/Port#Muskodus #Twexit #LongCovid #UrbanLoveWarrior #TootFinder #FamilyAbolitionist