Block anyone who diminishes your experience for any reason. You can block good people if they bother you. It's fine.
People get hung up on what it "means" to block or what "message" it sends, but forget all that. You're making the Internet that you want and nothing more.
I regularly mute people THAT I FOLLOW, temporarily, when they get off into some rabbit hole that irritates me. I temporarily mute topics that interest me if I get overwhelmed.
Reading the Internet is not your job.