Conversation

In 2019, another team reported that Porphyromonas gingivalis, a bacterium that causes gum disease, appears in the brains of Alzheimer’s patients. When repeatedly applied to the gums of mice, it appeared to trigger Alzheimer’s pathology in their brains, including excess amyloid beta. A year later came news that HSV-1 could cause Alzheimer’s-like changes in a 3D stem-cell derived tissue culture meant to model human brain tissue.

Science, 2 August 2024

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